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Rising cases of drug-induced liver injury (DILI) are raising concerns among health experts about the hidden dangers of common medications and supplements. According to a study published in Toxicology Reports, DILI, also known as toxic hepatitis, is a significant cause of acute liver failure, affecting about 20% of those prescribed medications.
Experts warn that herbal products, dietary supplements, and medications can trigger liver injury, especially in individuals with pre-existing liver conditions, nutritional deficiencies, or those who are pregnant. The liver's role in breaking down substances like supplements and medications can lead to increased risk if the process is slow, according to the American College of Gastroenterology.
Even FDA-approved medications can cause liver injury in rare cases. Common symptoms of liver disease include nausea, loss of appetite, abdominal pain, itching, dark urine, and jaundice, though some may not show signs.
A study identified turmeric, kratom, green tea extract, and Garcinia cambogia as supplements linked to potential liver toxicity. Cases of DILI from herbal or dietary supplements nearly tripled between 2004 and 2014, with these products being commonly implicated in severe and even fatal liver injury.
Dr. Marc Siegel, a senior medical analyst, highlighted the risks of herbal supplements, noting the lack of regulation in active chemical amounts, which can lead to increased liver toxicity. As the incidence of DILI continues to rise, awareness and caution are urged when using these common products.